Background: Blood oxygen saturation of vein (SvO2) is an important clinical parameter\nfor patient monitoring. However, the existing clinical methods are invasive, expensive,\nwhich are also painful for patients.\nMethods: Based on light-absorption, this study describes a new noninvasive SvO2\nmeasurement method by using external stimulation signal to generate cyclical fluctuation\nsignal in the vein, which overcomes the low signal-to-noise ratio problem in the\nmeasurement process. In this way, the value of SvO2 can be obtained continuously in\nreal time.\nResults: The experimental results demonstrate that the method can successfully\nmeasure venous oxygen saturation by artificial addition of stimulation. Under hypoxic\nconditions, the system can reflect the overall decline of venous oxygen saturation\nbetter. When the results measured by the new method are compared with those\nmeasured by the invasive method, the root mean square error of the difference is 5.31\nand the correlation coefficient of the difference is 0.72. The new method can be used\nto measure SvO2 and evaluate body oxygen consumption, and its accuracy needs\nimprovement.\nConclusions: Real-time and continuous monitoring can be achieved by replacing\ninvasive method with noninvasive method, which provides more comprehensive\nclinical information in a timely manner and better meet the needs of clinical treatment.\nHowever, the accuracy of the new noninvasive SvO2 measurement based on lightabsorption\nhas to be further improved.
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